Measurement of sleep-wakefulness cycle by sleep analysis program
It is difficult to evaluate sleep-wakefulness cycle in detail only by gross observation.
Electroencephalogram (EEG) analysis is a useful method for objectively evaluating sleep-wake cycles in experimental animals, which cannot verbally report their sleep status.
Analysis by dividing sleep stages into five can make it possible to observe the sleep cycle over time and to judge the sleep stage after administration of test articles. It is possible to evaluate not only sleep-wakefulness, but also epileptic seizures by detection of epilepsy EEG such as spike and simultaneous general condition observation.